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***CANCELLED: The Padwa Lecture - Abigail Doyle :CANCELLED***

Thursday, February 13, 2014 - 4:30pm - 5:30pm
Columbia University Morningside Campus Havemeyer Hall, Room 209



"Catalytic Strategies for Chemical Synthesis"

Presented by Abigail Doyle , Princeton

Hosted by Tristan Lambert

Thursday, February 13, 2014
Meet the Speaker at 1:30 Room 328 Havemeyer
Tea & Cookies at 4:00 Room 328 Havemeyer
Seminar at 4:30 Room 209 Havemeyer


My laboratory is engaged in the design of catalytic strategies to enable unprecedented bond-forming reactions with classic nucleophiles and electrophiles in organic synthesis. For example, we have discovered approaches to achieving the first catalytic methods for aliphatic nucleophilic fluorination. These pursuits have led to the identification of highly enantioselective methods for the synthesis of β-fluoro alcohols, cyclic allylic fluorides, acyclic allylic fluorides, and β-fluoro amines, versatile fluorinated chiral building blocks and important structural motifs for basic and biomedical science. On the other hand, we have developed a nickel-catalyzed cross-coupling platform to achieve previously impossible enantioselective CC bond-forming reactions with iminium and oxocarbenium ions, as well as epoxides and aziridines. This seminar will describe some of our recent progress in these areas.


Categories: Academic: Lecture